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Skincare guide

Niacinamide and vitamin C: can you use them together?

The truth behind the “niacinamide cancels vitamin C” myth — and how to combine these actives safely.

12/5/2025 niacinamidevitamin-cactives

Quick answer

Yes — niacinamide and vitamin C can be used in the same routine for most people, as long as you follow basic rules: start with moderate strengths, watch your skin, and avoid stacking too many strong actives at once.

Where the “conflict” myth came from

In older lab conditions (high heat + specific pH), some forms of pure ascorbic acid could react in ways that reduce stability. That scenario is unlikely on your bathroom shelf, and modern vitamin C derivatives are generally much more stable.

When the combo works great

  • Both actives are at moderate concentrations.
  • Your skin already tolerates each one separately.
  • Your routine has barrier basics: gentle cleansing, moisturizer, and daily SPF.

In this setup, the pair can complement each other for dullness, uneven tone, and mild pigmentation.

When to be more cautious

  • Very sensitive/reactive skin.
  • You also use acids and/or retinoids.
  • You start with high strengths right away (e.g., 10%+ niacinamide plus a “hot” vitamin C).

If that sounds like you, split actives by time (AM vs PM) or by days, and increase frequency gradually.

How BeautyAI helps

BeautyAI doesn’t look only at two keywords. It reviews the full INCI: acids, retinoids, buffers, potential irritants, fragrance, and alcohols. The bot can explain why a particular pair might be risky and suggest a gentler schedule.

Next step: check your actual products — you’ll get advice tailored to your real routine.

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